TB-500 5mg

TB-500 is a synthetic derivative of thymosin beta-4 (T????4). T????4 is a naturally occurring peptide composed of 43 amino acids. It is produced by the thymus gland and is found in body fluids, including saliva, blood, tears and wound fluid. Research shows that T????4 regulates various biological processes, such as cell differentiation, wound healing and tissue regeneration. The existing literature mentions research on T????4 only. As the structural analog of T????4, TB-500 is expected to replicate similar results.

Actin is a globular protein responsible for various cellular processes, including movement, cell shape and mechanical strength. Actin exists in two forms: G-actin and F-actin. G-actin monomers polymerize to form F-actin, which together with other proteins combine to form microfilaments. Thymosin beta 4 is an actin-sequestering molecule. It binds to G-actin and blocks its polymerization. Sequestering actin at the site of injury signals the body to migrate other stem and progenitor cells to the location, thus promoting connective tissue regeneration and healing. T????4 is also thought to reduce the expression of pro-inflammatory cytokines and microRNA-146a (miR-146a), thus suppressing inflammatory response.